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The HIV1 Protein Vpr Acts to Enhance Constitutive DCAF1-Dependent UNG2 Turnover

BACKGROUND: The HIV1 protein Vpr assembles with and acts through an ubiquitin ligase complex that includes DDB1 and cullin 4 (CRL4) to cause G2 cell cycle arrest and to promote degradation of both uracil DNA glycosylase 2 (UNG2) and single-strand selective mono-functional uracil DNA glycosylase 1 (S...

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Detalles Bibliográficos
Autores principales:	Wen, Xiaoyun, Casey Klockow, Laurieann, Nekorchuk, Michael, Sharifi, Hamayun J., de Noronha, Carlos M. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265533/ https://www.ncbi.nlm.nih.gov/pubmed/22292079 http://dx.doi.org/10.1371/journal.pone.0030939

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