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Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment

A fat-enriched diet modifies intestinal microbiota and initiates a low-grade inflammation, insulin resistance and type-2 diabetes. Here, we demonstrate that before the onset of diabetes, after only one week of a high-fat diet (HFD), live commensal intestinal bacteria are present in large numbers in...

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Detalles Bibliográficos
Autores principales: Amar, Jacques, Chabo, Chantal, Waget, Aurélie, Klopp, Pascale, Vachoux, Christelle, Bermúdez-Humarán, Luis G, Smirnova, Natalia, Bergé, Mathieu, Sulpice, Thierry, Lahtinen, Sampo, Ouwehand, Arthur, Langella, Philippe, Rautonen, Nina, Sansonetti, Philippe J, Burcelin, Rémy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265717/
https://www.ncbi.nlm.nih.gov/pubmed/21735552
http://dx.doi.org/10.1002/emmm.201100159