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Effect of trabectedin on the QT interval in patients with advanced solid tumor malignancies

PURPOSE: The primary objective of this study was to access the potential effects of trabectedin on the QT/QTc interval in patients with locally advanced or metastatic solid tumors. METHODS: Patients (n = 75) who had received ≤3 previous lines of chemotherapy and had either relapsed or had progressiv...

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Detalles Bibliográficos
Autores principales: Thertulien, R., Manikhas, G. M., Dirix, L. Y., Vermorken, J. B., Park, K., Jain, M. M., Jiao, J. J., Natarajan, J., Parekh, T., Zannikos, P., Staddon, A. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265736/
https://www.ncbi.nlm.nih.gov/pubmed/21739119
http://dx.doi.org/10.1007/s00280-011-1697-6