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Diacylglycerol kinase α controls RCP-dependent integrin trafficking to promote invasive migration

Inhibition of αvβ3 integrin or expression of oncogenic mutants of p53 promote invasive cell migration by enhancing endosomal recycling of α5β1 integrin under control of the Rab11 effector Rab-coupling protein (RCP). In this paper, we show that diacylglycerol kinase α (DGK-α), which phosphorylates di...

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Detalles Bibliográficos
Autores principales: Rainero, Elena, Caswell, Patrick T., Muller, Patricia A.J., Grindlay, Joan, McCaffrey, Mary W., Zhang, Qifeng, Wakelam, Michael J.O., Vousden, Karen H., Graziani, Andrea, Norman, Jim C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265946/
https://www.ncbi.nlm.nih.gov/pubmed/22270919
http://dx.doi.org/10.1083/jcb.201109112