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Diacylglycerol kinase α controls RCP-dependent integrin trafficking to promote invasive migration
Inhibition of αvβ3 integrin or expression of oncogenic mutants of p53 promote invasive cell migration by enhancing endosomal recycling of α5β1 integrin under control of the Rab11 effector Rab-coupling protein (RCP). In this paper, we show that diacylglycerol kinase α (DGK-α), which phosphorylates di...
Autores principales: | Rainero, Elena, Caswell, Patrick T., Muller, Patricia A.J., Grindlay, Joan, McCaffrey, Mary W., Zhang, Qifeng, Wakelam, Michael J.O., Vousden, Karen H., Graziani, Andrea, Norman, Jim C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265946/ https://www.ncbi.nlm.nih.gov/pubmed/22270919 http://dx.doi.org/10.1083/jcb.201109112 |
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