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FAK promotes recruitment of talin to nascent adhesions to control cell motility

Cell migration is a dynamic process that involves the continuous formation, maturation, and turnover of matrix–cell adhesion sites. New (nascent) adhesions form at the protruding cell edge in a tension-independent manner and are comprised of integrin receptors, signaling, and cytoskeletal-associated...

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Detalles Bibliográficos
Autores principales: Lawson, Christine, Lim, Ssang-Taek, Uryu, Sean, Chen, Xiao Lei, Calderwood, David A., Schlaepfer, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265949/
https://www.ncbi.nlm.nih.gov/pubmed/22270917
http://dx.doi.org/10.1083/jcb.201108078