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The dynamics of replication licensing in live Caenorhabditis elegans embryos

Accurate DNA replication requires proper regulation of replication licensing, which entails loading MCM-2–7 onto replication origins. In this paper, we provide the first comprehensive view of replication licensing in vivo, using video microscopy of Caenorhabditis elegans embryos. As expected, MCM-2–...

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Detalles Bibliográficos
Autores principales: Sonneville, Remi, Querenet, Matthieu, Craig, Ashley, Gartner, Anton, Blow, J. Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265957/
https://www.ncbi.nlm.nih.gov/pubmed/22249291
http://dx.doi.org/10.1083/jcb.201110080