Folate-mediated targeted and intracellular delivery of paclitaxel using a novel deoxycholic acid-O-carboxymethylated chitosan–folic acid micelles

BACKGROUND: A critical disadvantage for successful chemotherapy with paclitaxel (PTX) is its nontargeting nature to cancer cells. Folic acid has been employed as a targeting ligand of various anticancer agents to increase their cellular uptake within target cells since the folate receptor is overexp...

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Detalles Bibliográficos
Autores principales: Wang, Feihu, Chen, Yuxuan, Zhang, Dianrui, Zhang, Qiang, Zheng, Dandan, Hao, Leilei, Liu, Yue, Duan, Cunxian, Jia, Lejiao, Liu, Guangpu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266000/
https://www.ncbi.nlm.nih.gov/pubmed/22287842
http://dx.doi.org/10.2147/IJN.S27823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266000/
https://www.ncbi.nlm.nih.gov/pubmed/22287842
http://dx.doi.org/10.2147/IJN.S27823

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