Disorder-specific effects of polymorphisms at opposing ends of the Insulin Degrading Enzyme gene

BACKGROUND: Insulin-degrading enzyme (IDE) is the ubiquitously expressed enzyme responsible for insulin and amyloid beta (Aβ) degradation. IDE gene is located on chromosome region 10q23-q25 and exhibits a well-replicated peak of linkage with Type 2 diabetes mellitus (T2DM). Several genetic associati...

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Detalles Bibliográficos
Autores principales: Bartl, Jasmin, Scholz, Claus-Jürgen, Hinterberger, Margareta, Jungwirth, Susanne, Wichart, Ildiko, Rainer, Michael K, Kneitz, Susanne, Danielczyk, Walter, Tragl, Karl H, Fischer, Peter, Riederer, Peter, Grünblatt, Edna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266204/
https://www.ncbi.nlm.nih.gov/pubmed/22107728
http://dx.doi.org/10.1186/1471-2350-12-151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266204/
https://www.ncbi.nlm.nih.gov/pubmed/22107728
http://dx.doi.org/10.1186/1471-2350-12-151

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