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Helicobacter pylori vacuolating toxin A and apoptosis

VacA, the vacuolating cytotoxin A of Helicobacter pylori, induces apoptosis in epithelial cells of the gastic mucosa and in leukocytes. VacA is released by the bacteria as a protein of 88 kDa. At the outer surface of host cells, it binds to the sphingomyelin of lipid rafts. At least partially, bindi...

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Detalles Bibliográficos
Autor principal: Rassow, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266207/
https://www.ncbi.nlm.nih.gov/pubmed/22044628
http://dx.doi.org/10.1186/1478-811X-9-26