Cargando…

Transient Ureteral Obstruction Prevents against Kidney Ischemia/Reperfusion Injury via Hypoxia-Inducible Factor (HIF)-2α Activation

Although the protective effect of transient ureteral obstruction (UO) prior to ischemia on subsequent renal ischemia/reperfusion (I/R) injury has been documented, the underlying molecular mechanism remains to be understood. We showed in the current study that 24 h of UO led to renal tubular hypoxia...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Shun, Han, Cong-Hui, Chen, Xiao-Song, Zhang, Ming, Xu, Long-Mei, Zhang, Jian-Jun, Xia, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266244/
https://www.ncbi.nlm.nih.gov/pubmed/22295069
http://dx.doi.org/10.1371/journal.pone.0029876