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The Ankyrin Repeat Domain of the TRPA Protein Painless Is Important for Thermal Nociception but Not Mechanical Nociception

The Drosophila TRPA channel Painless is required for the function of polymodal nociceptors which detect noxious heat and noxious mechanical stimuli. These functions of Painless are reminiscent of mammalian TRPA channels that have also been implicated in thermal and mechanical nociception. A popular...

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Detalles Bibliográficos
Autores principales: Hwang, Richard Y., Stearns, Nancy A., Tracey, W. Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266251/
https://www.ncbi.nlm.nih.gov/pubmed/22295071
http://dx.doi.org/10.1371/journal.pone.0030090