Ablation of NG2 Proteoglycan Leads to Deficits in Brown Fat Function and to Adult Onset Obesity

Obesity is a major health problem worldwide. We are studying the causes and effects of obesity in C57Bl/6 mice following genetic ablation of NG2, a chondroitin sulfate proteoglycan widely expressed in progenitor cells and also in adipocytes. Although global NG2 ablation delays early postnatal adipog...

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Detalles Bibliográficos
Autores principales: Chang, Yunchao, She, Zhi-Gang, Sakimura, Kenji, Roberts, Amanda, Kucharova, Karolina, Rowitch, David H., Stallcup, William B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266271/
https://www.ncbi.nlm.nih.gov/pubmed/22295099
http://dx.doi.org/10.1371/journal.pone.0030637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266271/
https://www.ncbi.nlm.nih.gov/pubmed/22295099
http://dx.doi.org/10.1371/journal.pone.0030637

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