A Plasma Survey Using 38 PfEMP1 Domains Reveals Frequent Recognition of the Plasmodium falciparum Antigen VAR2CSA among Young Tanzanian Children

PfEMP1 proteins comprise a family of variant antigens that appear on the surface of P. falciparum-infected erythrocytes and bind to multiple host receptors. Using a mammalian expression system and BioPlex technology, we developed an array of 24 protein constructs representing 38 PfEMP1 domains for h...

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Detalles Bibliográficos
Autores principales: Oleinikov, Andrew V., Voronkova, Valentina V., Frye, Isaac Tyler, Amos, Emily, Morrison, Robert, Fried, Michal, Duffy, Patrick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266279/
https://www.ncbi.nlm.nih.gov/pubmed/22295123
http://dx.doi.org/10.1371/journal.pone.0031011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266279/
https://www.ncbi.nlm.nih.gov/pubmed/22295123
http://dx.doi.org/10.1371/journal.pone.0031011

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