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A Plasma Survey Using 38 PfEMP1 Domains Reveals Frequent Recognition of the Plasmodium falciparum Antigen VAR2CSA among Young Tanzanian Children
PfEMP1 proteins comprise a family of variant antigens that appear on the surface of P. falciparum-infected erythrocytes and bind to multiple host receptors. Using a mammalian expression system and BioPlex technology, we developed an array of 24 protein constructs representing 38 PfEMP1 domains for h...
Autores principales: | Oleinikov, Andrew V., Voronkova, Valentina V., Frye, Isaac Tyler, Amos, Emily, Morrison, Robert, Fried, Michal, Duffy, Patrick E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266279/ https://www.ncbi.nlm.nih.gov/pubmed/22295123 http://dx.doi.org/10.1371/journal.pone.0031011 |
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