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microRNA-152 Mediates DNMT1-Regulated DNA Methylation in the Estrogen Receptor α Gene

BACKGROUND: Estrogen receptor α (ERα) has been shown to protect against atherosclerosis. Methylation of the ERα gene can reduce ERα expression leading to a higher risk for cardiovascular disease. Recently, microRNAs have been found to regulate DNA methyltransferases (DNMTs) and thus control methylat...

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Detalles Bibliográficos
Autores principales: Wang, Yung-Song, Chou, Wen-Wen, Chen, Ku-Chung, Cheng, Hsin-Yun, Lin, Ruey-Tay, Juo, Suh-Hang Hank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266286/
https://www.ncbi.nlm.nih.gov/pubmed/22295098
http://dx.doi.org/10.1371/journal.pone.0030635