Elevated Pontine and Putamenal GABA Levels in Mild-Moderate Parkinson Disease Detected by 7 Tesla Proton MRS

BACKGROUND: Parkinson disease (PD) is characterized by the degeneration of nigrostriatal dopaminergic neurons. However, postmortem evidence indicates that the pathology of lower brainstem regions, such as the pons and medulla, precedes nigral involvement. Consistently, pontomedullary damage was impl...

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Detalles Bibliográficos
Autores principales: Emir, Uzay E., Tuite, Paul J., Öz, Gülin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266292/
https://www.ncbi.nlm.nih.gov/pubmed/22295119
http://dx.doi.org/10.1371/journal.pone.0030918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266292/
https://www.ncbi.nlm.nih.gov/pubmed/22295119
http://dx.doi.org/10.1371/journal.pone.0030918

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