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Co-Infection with the Friend Retrovirus and Mouse Scrapie Does Not Alter Prion Disease Pathogenesis in Susceptible Mice

Prion diseases are fatal, transmissible neurodegenerative diseases of the central nervous system. An abnormally protease-resistant and insoluble form (PrP(Sc)) of the normally soluble protease-sensitive host prion protein (PrP(C)) is the major component of the infectious prion. During the course of...

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Detalles Bibliográficos
Autores principales: Leblanc, Pascal, Hasenkrug, Kim, Ward, Anne, Myers, Lara, Messer, Ronald J., Alais, Sandrine, Timmes, Andrew, Priola, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266293/
https://www.ncbi.nlm.nih.gov/pubmed/22295118
http://dx.doi.org/10.1371/journal.pone.0030872