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Morbidly Obese Human Subjects Have Increased Peripheral Blood CD4(+) T Cells With Skewing Toward a Treg- and Th2-Dominated Phenotype

Obesity is associated with local T-cell abnormalities in adipose tissue. Systemic obesity-related abnormalities in the peripheral blood T-cell compartment are not well defined. In this study, we investigated the peripheral blood T-cell compartment of morbidly obese and lean subjects. We determined a...

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Detalles Bibliográficos
Autores principales: van der Weerd, Kim, Dik, Willem A., Schrijver, Benjamin, Schweitzer, Dave H., Langerak, Anton W., Drexhage, Hemmo A., Kiewiet, Rosalie M., van Aken, Maarten O., van Huisstede, Astrid, van Dongen, Jacques J.M., van der Lelij, Aart-Jan, Staal, Frank J.T., van Hagen, P. Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266399/
https://www.ncbi.nlm.nih.gov/pubmed/22228716
http://dx.doi.org/10.2337/db11-1065