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Brain Glucose Sensors Play a Significant Role in the Regulation of Pancreatic Glucose-Stimulated Insulin Secretion

As patients decline from health to type 2 diabetes, glucose-stimulated insulin secretion (GSIS) typically becomes impaired. Although GSIS is driven predominantly by direct sensing of a rise in blood glucose by pancreatic β-cells, there is growing evidence that hypothalamic neurons control other aspe...

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Detalles Bibliográficos
Autores principales: Osundiji, Mayowa A., Lam, Daniel D., Shaw, Jill, Yueh, Chen-Yu, Markkula, S. Pauliina, Hurst, Paul, Colliva, Carolina, Roda, Aldo, Heisler, Lora K., Evans, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266403/
https://www.ncbi.nlm.nih.gov/pubmed/22210318
http://dx.doi.org/10.2337/db11-1050