l-Leucine Alters Pancreatic β-Cell Differentiation and Function via the mTor Signaling Pathway

Leucine (Leu) is an essential branched-chain amino acid, which activates the mammalian target of rapamycin (mTOR) signaling pathway. The effect of Leu on cell differentiation during embryonic development is unknown. Here, we show that Leu supplementation during pregnancy significantly increased feta...

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Detalles Bibliográficos
Autores principales: Rachdi, Latif, Aïello, Virginie, Duvillié, Bertrand, Scharfmann, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266409/
https://www.ncbi.nlm.nih.gov/pubmed/22210321
http://dx.doi.org/10.2337/db11-0765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266409/
https://www.ncbi.nlm.nih.gov/pubmed/22210321
http://dx.doi.org/10.2337/db11-0765

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