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Potential Role of Tumor Necrosis Factor-α in Downregulating Sex Hormone–Binding Globulin
Low plasma sex hormone–binding globulin (SHBG) levels are associated with obesity and predict the development of type 2 diabetes. The reason why obese individuals have low circulating SHBG has been attributed to hyperinsulinemia, but no mechanistic evidence has been described. The aim of the current...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266423/ https://www.ncbi.nlm.nih.gov/pubmed/22210320 http://dx.doi.org/10.2337/db11-0727 |