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Bcl-2–Modifying Factor Induces Renal Proximal Tubular Cell Apoptosis in Diabetic Mice

This study investigated the mechanisms underlying tubular apoptosis in diabetes by identifying proapoptotic genes that are differentially upregulated by reactive oxygen species in renal proximal tubular cells (RPTCs) in models of diabetes. Total RNAs isolated from renal proximal tubules (RPTs) of 20...

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Detalles Bibliográficos
Autores principales: Lau, Garnet J., Godin, Nicolas, Maachi, Hasna, Lo, Chao-Sheng, Wu, Shyh-Jong, Zhu, Jian-Xin, Brezniceanu, Marie-Luise, Chénier, Isabelle, Fragasso-Marquis, Joelle, Lattouf, Jean-Baptiste, Ethier, Jean, Filep, Janos G., Ingelfinger, Julie R., Nair, Viji, Kretzler, Matthias, Cohen, Clemens D., Zhang, Shao-Ling, Chan, John S.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266424/
https://www.ncbi.nlm.nih.gov/pubmed/22210314
http://dx.doi.org/10.2337/db11-0141