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Bcl-2–Modifying Factor Induces Renal Proximal Tubular Cell Apoptosis in Diabetic Mice
This study investigated the mechanisms underlying tubular apoptosis in diabetes by identifying proapoptotic genes that are differentially upregulated by reactive oxygen species in renal proximal tubular cells (RPTCs) in models of diabetes. Total RNAs isolated from renal proximal tubules (RPTs) of 20...
Autores principales: | Lau, Garnet J., Godin, Nicolas, Maachi, Hasna, Lo, Chao-Sheng, Wu, Shyh-Jong, Zhu, Jian-Xin, Brezniceanu, Marie-Luise, Chénier, Isabelle, Fragasso-Marquis, Joelle, Lattouf, Jean-Baptiste, Ethier, Jean, Filep, Janos G., Ingelfinger, Julie R., Nair, Viji, Kretzler, Matthias, Cohen, Clemens D., Zhang, Shao-Ling, Chan, John S.D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266424/ https://www.ncbi.nlm.nih.gov/pubmed/22210314 http://dx.doi.org/10.2337/db11-0141 |
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