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Postnatal Growth and DNA Methylation Are Associated With Differential Gene Expression of the TACSTD2 Gene and Childhood Fat Mass

Rapid postnatal growth is associated with increased risk of childhood adiposity. The aim of this study was to establish whether this pathway is mediated by altered DNA methylation and gene expression. Two distinct cohorts, one preterm (n = 121) and one term born (n = 6,990), were studied. Explorator...

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Detalles Bibliográficos
Autores principales: Groom, Alexandra, Potter, Catherine, Swan, Daniel C., Fatemifar, Ghazaleh, Evans, David M., Ring, Susan M., Turcot, Valerie, Pearce, Mark S., Embleton, Nicholas D., Davey Smith, George, Mathers, John C., Relton, Caroline L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266428/
https://www.ncbi.nlm.nih.gov/pubmed/22190649
http://dx.doi.org/10.2337/db11-1039