Functional Analysis of APOE Locus Genetic Variation Implicates Regional Enhancers in the Regulation of Both TOMM40 and APOE

Genetic variation within the apolipoprotein E gene (APOE) locus is associated with late-onset Alzheimer's disease risk and quantitative traits as well as apoE expression in multiple tissues. The aim of this investigation was to explore the influence of APOE locus cis-regulatory element enhancer...

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Detalles Bibliográficos
Autores principales: Bekris, L.M., Lutz, F., Yu, C.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266441/
https://www.ncbi.nlm.nih.gov/pubmed/22089642
http://dx.doi.org/10.1038/jhg.2011.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266441/
https://www.ncbi.nlm.nih.gov/pubmed/22089642
http://dx.doi.org/10.1038/jhg.2011.123

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