Bovine AAV Transcytosis Inhibition by Tannic Acid Results in Functional Expression of CFTR in Vitro and Altered Bio-Distribution in Vivo

Bovine Adeno-Associated Virus (BAAV) can enter a cell either through a transcytosis or transduction pathway. We previously demonstrated that particles entering via the transcytosis pathway can be redirected to transduce the cell by blocking particle exocytosis with tannic acid (TA). To investigate w...

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Detalles Bibliográficos
Autores principales: Di Pasquale, Giovanni, Ostedgaard, Lynda, Vermeer, Daniel, Swaim, William D., Karp, Philip, Chiorini, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266448/
https://www.ncbi.nlm.nih.gov/pubmed/22011646
http://dx.doi.org/10.1038/gt.2011.138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266448/
https://www.ncbi.nlm.nih.gov/pubmed/22011646
http://dx.doi.org/10.1038/gt.2011.138

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