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Bovine AAV Transcytosis Inhibition by Tannic Acid Results in Functional Expression of CFTR in Vitro and Altered Bio-Distribution in Vivo
Bovine Adeno-Associated Virus (BAAV) can enter a cell either through a transcytosis or transduction pathway. We previously demonstrated that particles entering via the transcytosis pathway can be redirected to transduce the cell by blocking particle exocytosis with tannic acid (TA). To investigate w...
Autores principales: | Di Pasquale, Giovanni, Ostedgaard, Lynda, Vermeer, Daniel, Swaim, William D., Karp, Philip, Chiorini, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266448/ https://www.ncbi.nlm.nih.gov/pubmed/22011646 http://dx.doi.org/10.1038/gt.2011.138 |
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