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Phospholipase Cγ2 is required for basal but not oestrogen deficiency–induced bone resorption

BACKGROUND: Osteoclasts play a critical role in bone resorption under basal conditions, but they also contribute to pathological bone loss during diseases including postmenopausal osteoporosis. Phospholipase Cγ2 (PLCγ2) is an important signalling molecule in diverse haematopoietic lineages. Here, we...

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Detalles Bibliográficos
Autores principales: Kertész, Zsuzsanna, Győri, Dávid, Körmendi, Szandra, Fekete, Tünde, Kis-Tóth, Katalin, Jakus, Zoltán, Schett, Georg, Rajnavölgyi, Éva, Dobó-Nagy, Csaba, Mócsai, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266491/
https://www.ncbi.nlm.nih.gov/pubmed/21749368
http://dx.doi.org/10.1111/j.1365-2362.2011.02556.x