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Phospholipase Cγ2 is required for basal but not oestrogen deficiency–induced bone resorption
BACKGROUND: Osteoclasts play a critical role in bone resorption under basal conditions, but they also contribute to pathological bone loss during diseases including postmenopausal osteoporosis. Phospholipase Cγ2 (PLCγ2) is an important signalling molecule in diverse haematopoietic lineages. Here, we...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266491/ https://www.ncbi.nlm.nih.gov/pubmed/21749368 http://dx.doi.org/10.1111/j.1365-2362.2011.02556.x |