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Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells

Polyamines spermidine and spermine are known to be required for mammalian cell proliferation and for embryonic development. Alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase (ODC) a limiting enzyme of polyamine biosynthesis, depleted the cellular polyamines and prevented...

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Detalles Bibliográficos
Autores principales: Ishii, Ikumi, Ikeguchi, Yoshihiko, Mano, Hiroshi, Wada, Masahiro, Pegg, Anthony E., Shirahata, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266501/
https://www.ncbi.nlm.nih.gov/pubmed/21809076
http://dx.doi.org/10.1007/s00726-011-1037-5