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Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells
Polyamines spermidine and spermine are known to be required for mammalian cell proliferation and for embryonic development. Alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase (ODC) a limiting enzyme of polyamine biosynthesis, depleted the cellular polyamines and prevented...
Autores principales: | Ishii, Ikumi, Ikeguchi, Yoshihiko, Mano, Hiroshi, Wada, Masahiro, Pegg, Anthony E., Shirahata, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266501/ https://www.ncbi.nlm.nih.gov/pubmed/21809076 http://dx.doi.org/10.1007/s00726-011-1037-5 |
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