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Structural insights into human Kif7, a kinesin involved in Hedgehog signalling
Kif7, a member of the kinesin 4 superfamily, is implicated in a variety of diseases including Joubert, hydrolethalus and acrocallosal syndromes. It is also involved in primary cilium formation and the Hedgehog signalling pathway and may play a role in cancer. Its activity is crucial for embryonic de...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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International Union of Crystallography
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266853/ https://www.ncbi.nlm.nih.gov/pubmed/22281744 http://dx.doi.org/10.1107/S0907444911053042 |