NKT Cell Stimulation with α-Galactosylceramide Results in a Block of Th17 Differentiation after Intranasal Immunization in Mice

In a previous study we demonstrated that intranasal (i.n.) vaccination promotes a Th17 biased immune response. Here, we show that co-administration of a pegylated derivative of α-galactosylceramide (αGCPEG) with an antigen, even in the presence of Th17-polarizing compounds, results in a strong block...

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Detalles Bibliográficos
Autores principales: Zygmunt, Beata M., Weissmann, Sebastian F., Guzman, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266900/
https://www.ncbi.nlm.nih.gov/pubmed/22291945
http://dx.doi.org/10.1371/journal.pone.0030382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266900/
https://www.ncbi.nlm.nih.gov/pubmed/22291945
http://dx.doi.org/10.1371/journal.pone.0030382

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