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Persistence of Cytosine Methylation of DNA following Fertilisation in the Mouse
Normal development of the mammalian embryo requires epigenetic reprogramming of the genome. The level of cytosine methylation of CpG-rich (5meC) regions of the genome is a major epigenetic regulator and active global demethylation of 5meC throughout the genome is reported to occur within the first c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266909/ https://www.ncbi.nlm.nih.gov/pubmed/22292019 http://dx.doi.org/10.1371/journal.pone.0030687 |