IL-10R Blockade during Chronic Schistosomiasis Mansoni Results in the Loss of B Cells from the Liver and the Development of Severe Pulmonary Disease

In schistosomiasis patients, parasite eggs trapped in hepatic sinusoids become foci for CD4(+) T cell-orchestrated granulomatous cellular infiltrates. Since the immune response is unable to clear the infection, the liver is subjected to ongoing cycles of focal inflammation and healing that lead to v...

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Detalles Bibliográficos
Autores principales: Fairfax, Keke C., Amiel, Eyal, King, Irah L., Freitas, Tori C., Mohrs, Markus, Pearce, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266936/
https://www.ncbi.nlm.nih.gov/pubmed/22291593
http://dx.doi.org/10.1371/journal.ppat.1002490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266936/
https://www.ncbi.nlm.nih.gov/pubmed/22291593
http://dx.doi.org/10.1371/journal.ppat.1002490

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