Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration

It is of urgent need to identify the exact physico-chemical characteristics which allow maximum uptake and accumulation in secondary target organs of nanoparticulate drug delivery systems after oral ingestion. We administered radiolabelled gold nanoparticles in different sizes (1.4-200 nm) with nega...

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Detalles Bibliográficos
Autores principales: Schleh, Carsten, Semmler-Behnke, Manuela, Lipka, Jens, Wenk, Alexander, Hirn, Stephanie, Schäffler, Martin, Schmid, Günter, Simon, Ulrich, Kreyling, Wolfgang G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267526/
https://www.ncbi.nlm.nih.gov/pubmed/21309618
http://dx.doi.org/10.3109/17435390.2011.552811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267526/
https://www.ncbi.nlm.nih.gov/pubmed/21309618
http://dx.doi.org/10.3109/17435390.2011.552811

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