DNA building blocks: keeping control of manufacture

Ribonucleotide reductase (RNR) is the only source for de novo production of the four deoxyribonucleoside triphosphate (dNTP) building blocks needed for DNA synthesis and repair. It is crucial that these dNTP pools are carefully balanced, since mutation rates increase when dNTP levels are either unba...

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Detalles Bibliográficos
Autores principales: Hofer, Anders, Crona, Mikael, Logan, Derek T, Sjöberg, Britt-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267527/
https://www.ncbi.nlm.nih.gov/pubmed/22050358
http://dx.doi.org/10.3109/10409238.2011.630372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267527/
https://www.ncbi.nlm.nih.gov/pubmed/22050358
http://dx.doi.org/10.3109/10409238.2011.630372

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