Osteogenesis imperfecta: the audiological phenotype lacks correlation with the genotype

BACKGROUND: Osteogenesis Imperfecta (OI) is a heritable connective tissue disorder mainly caused by mutations in the genes COL1A1 and COL1A2 and is associated with hearing loss in approximately half of the cases. The hearing impairment usually starts between the second and fourth decade of life as a...

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Detalles Bibliográficos
Autores principales: Swinnen, Freya KR, Coucke, Paul J, De Paepe, Anne M, Symoens, Sofie, Malfait, Fransiska, Gentile, Filomena V, Sangiorgi, Luca, D'Eufemia, Patrizia, Celli, Mauro, Garretsen, Ton JTM, Cremers, Cor WRJ, Dhooge, Ingeborg JM, De Leenheer, Els MR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267664/
https://www.ncbi.nlm.nih.gov/pubmed/22206639
http://dx.doi.org/10.1186/1750-1172-6-88

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267664/
https://www.ncbi.nlm.nih.gov/pubmed/22206639
http://dx.doi.org/10.1186/1750-1172-6-88

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