The role of ALOX5AP, LTA4H and LTB4R polymorphisms in determining baseline lung function and COPD susceptibility in UK smokers

BACKGROUND: We have previously shown evidence that polymorphisms within genes controlling leukotriene B(4 )(LTB(4)) production (ALOX5AP and LTA4H) are associated with asthma susceptibility in children. Evidence also suggests a potential role of LTB(4 )in COPD disease mechanisms including recruitment...

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Detalles Bibliográficos
Autores principales: Tulah, Asif S, Parker, Stuart G, Moffatt, Miriam F, Wardlaw, Andrew J, Connolly, Martin J, Sayers, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267686/
https://www.ncbi.nlm.nih.gov/pubmed/22206291
http://dx.doi.org/10.1186/1471-2350-12-173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267686/
https://www.ncbi.nlm.nih.gov/pubmed/22206291
http://dx.doi.org/10.1186/1471-2350-12-173

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