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The role of ALOX5AP, LTA4H and LTB4R polymorphisms in determining baseline lung function and COPD susceptibility in UK smokers
BACKGROUND: We have previously shown evidence that polymorphisms within genes controlling leukotriene B(4 )(LTB(4)) production (ALOX5AP and LTA4H) are associated with asthma susceptibility in children. Evidence also suggests a potential role of LTB(4 )in COPD disease mechanisms including recruitment...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267686/ https://www.ncbi.nlm.nih.gov/pubmed/22206291 http://dx.doi.org/10.1186/1471-2350-12-173 |