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Class II MHC Self-Antigen Presentation in Human B and T Lymphocytes
Human CD4(+) T cells process and present functional class II MHC-peptide complexes, but the endogenous peptide repertoire of these non-classical antigen presenting cells remains unknown. We eluted and sequenced HLA-DR-bound self-peptides presented by CD4(+) T cells in order to compare the T cell-der...
Autores principales: | Costantino, Cristina Maria, Spooner, Eric, Ploegh, Hidde L., Hafler, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267721/ https://www.ncbi.nlm.nih.gov/pubmed/22299025 http://dx.doi.org/10.1371/journal.pone.0029805 |
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