BMP-9 Induced Endothelial Cell Tubule Formation and Inhibition of Migration Involves Smad1 Driven Endothelin-1 Production

BACKGROUND: Bone morphogenetic proteins (BMPs) and their receptors, such as bone morphogenetic protein receptor (BMPR) II, have been implicated in a wide variety of disorders including pulmonary arterial hypertension (PAH). Similarly, endothelin-1 (ET-1), a mitogen and vasoconstrictor, is upregulate...

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Detalles Bibliográficos
Autores principales: Park, John E. S., Shao, Dongmin, Upton, Paul D., deSouza, Patricia, Adcock, Ian M., Davies, Rachel J., Morrell, Nicholas W., Griffiths, Mark J. D., Wort, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267722/
https://www.ncbi.nlm.nih.gov/pubmed/22299030
http://dx.doi.org/10.1371/journal.pone.0030075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267722/
https://www.ncbi.nlm.nih.gov/pubmed/22299030
http://dx.doi.org/10.1371/journal.pone.0030075

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