Ashwagandha Derived Withanone Targets TPX2-Aurora A Complex: Computational and Experimental Evidence to its Anticancer Activity

Cancer is largely marked by genetic instability. Specific inhibition of individual proteins or signalling pathways that regulate genetic stability during cell division thus hold a great potential for cancer therapy. The Aurora A kinase is a Ser/Thr kinase that plays a critical role during mitosis an...

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Detalles Bibliográficos
Autores principales: Grover, Abhinav, Singh, Rumani, Shandilya, Ashutosh, Priyandoko, Didik, Agrawal, Vibhuti, Bisaria, Virendra S., Wadhwa, Renu, Kaul, Sunil C., Sundar, Durai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267739/
https://www.ncbi.nlm.nih.gov/pubmed/22303466
http://dx.doi.org/10.1371/journal.pone.0030890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267739/
https://www.ncbi.nlm.nih.gov/pubmed/22303466
http://dx.doi.org/10.1371/journal.pone.0030890

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