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Coxiella burnetii Induces Apoptosis during Early Stage Infection via a Caspase-Independent Pathway in Human Monocytic THP-1 Cells

The ability of Coxiella burnetii to modulate host cell death may be a critical factor in disease development. In this study, human monocytic THP-1 cells were used to examine the ability of C. burnetii Nine Mile phase II (NMII) to modulate apoptotic signaling. Typical apoptotic cell morphological cha...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Zhang, Guoquan, Hendrix, Laura R., Tesh, Vernon L., Samuel, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267756/
https://www.ncbi.nlm.nih.gov/pubmed/22303462
http://dx.doi.org/10.1371/journal.pone.0030841