PKCθ Synergizes with TLR-Dependent TRAF6 Signaling Pathway to Upregulate MUC5AC Mucin via CARMA1

CARD-containing MAGUK protein 1 (CARMA1) plays a crucial role in regulating adaptive immune responses upon T-cell receptor (TCR) activation in T cells. Its role in regulating host mucosal innate immune response such as upregulation of mucin remains unknown. Here we show that CARMA1 acts as a key sig...

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Detalles Bibliográficos
Autores principales: Jono, Hirofumi, Lim, Jae Hyang, Xu, Haidong, Li, Jian-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267763/
https://www.ncbi.nlm.nih.gov/pubmed/22303480
http://dx.doi.org/10.1371/journal.pone.0031049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267763/
https://www.ncbi.nlm.nih.gov/pubmed/22303480
http://dx.doi.org/10.1371/journal.pone.0031049

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