Quantitating subcellular metabolism with multi-isotope imaging mass spectrometry

Mass spectrometry with stable isotope labels has been seminal in discovering the dynamic state of living matter(1,2) but is limited to bulk tissues or cells. We developed multi-isotope imaging mass spectrometry (MIMS) that allowed us to view and measure stable isotope incorporation with sub-micron r...

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Detalles Bibliográficos
Autores principales: Steinhauser, Matthew L., Bailey, Andrew, Senyo, Samuel E., Guillermier, Christelle, Perlstein, Todd S., Gould, Alex P., Lee, Richard T., Lechene, Claude P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267887/
https://www.ncbi.nlm.nih.gov/pubmed/22246326
http://dx.doi.org/10.1038/nature10734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267887/
https://www.ncbi.nlm.nih.gov/pubmed/22246326
http://dx.doi.org/10.1038/nature10734

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