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Quantitating subcellular metabolism with multi-isotope imaging mass spectrometry
Mass spectrometry with stable isotope labels has been seminal in discovering the dynamic state of living matter(1,2) but is limited to bulk tissues or cells. We developed multi-isotope imaging mass spectrometry (MIMS) that allowed us to view and measure stable isotope incorporation with sub-micron r...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267887/ https://www.ncbi.nlm.nih.gov/pubmed/22246326 http://dx.doi.org/10.1038/nature10734 |