Functional hyper-IL-6 from vaccinia virus-colonized tumors triggers platelet formation and helps to alleviate toxicity of mitomycin C enhanced virus therapy

BACKGROUND: Combination of oncolytic vaccinia virus therapy with conventional chemotherapy has shown promise for tumor therapy. However, side effects of chemotherapy including thrombocytopenia, still remain problematic. METHODS: Here, we describe a novel approach to optimize combination therapy of o...

Descripción completa

Detalles Bibliográficos
Autores principales: Sturm, Julia B, Hess, Michael, Weibel, Stephanie, Chen, Nanhai G, Yu, Yong A, Zhang, Qian, Donat, Ulrike, Reiss, Cora, Gambaryan, Stepan, Krohne, Georg, Stritzker, Jochen, Szalay, Aladar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268093/
https://www.ncbi.nlm.nih.gov/pubmed/22236378
http://dx.doi.org/10.1186/1479-5876-10-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268093/
https://www.ncbi.nlm.nih.gov/pubmed/22236378
http://dx.doi.org/10.1186/1479-5876-10-9

Ejemplares similares