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Functional hyper-IL-6 from vaccinia virus-colonized tumors triggers platelet formation and helps to alleviate toxicity of mitomycin C enhanced virus therapy

BACKGROUND: Combination of oncolytic vaccinia virus therapy with conventional chemotherapy has shown promise for tumor therapy. However, side effects of chemotherapy including thrombocytopenia, still remain problematic. METHODS: Here, we describe a novel approach to optimize combination therapy of o...

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Detalles Bibliográficos
Autores principales:	Sturm, Julia B, Hess, Michael, Weibel, Stephanie, Chen, Nanhai G, Yu, Yong A, Zhang, Qian, Donat, Ulrike, Reiss, Cora, Gambaryan, Stepan, Krohne, Georg, Stritzker, Jochen, Szalay, Aladar A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268093/ https://www.ncbi.nlm.nih.gov/pubmed/22236378 http://dx.doi.org/10.1186/1479-5876-10-9

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