Cargando…

Cardiac dysfunction in adipose triglyceride lipase deficiency: treatment with a PPARα agonist

BACKGROUND AND PURPOSE: Adipose triglyceride lipase (ATGL) has been identified as a rate-limiting enzyme of mammalian triglyceride catabolism. Deletion of the ATGL gene in mice results in severe lipid accumulation in a variety of tissues including the heart. In the present study we investigated card...

Descripción completa

Detalles Bibliográficos
Autores principales: Wölkart, G, Schrammel, A, Dörffel, K, Haemmerle, G, Zechner, R, Mayer, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268192/
https://www.ncbi.nlm.nih.gov/pubmed/21585347
http://dx.doi.org/10.1111/j.1476-5381.2011.01490.x